Restraint Nose

exposure equipment

​​Exposure Chambers

In-Tox Products manufactures a well-known Cylindrical Inhalation Chamber used in laboratories around the world. The Chamber is used for the delivery of aerosols to laboratory animals under controlled conditions to assess the toxicity of aerosols or vapors. The chambers are available in several port sizes: 6, 12, 24, 36, 48, and 72 Port Chambers. The chamber is mounted on a carousel base which can be rotated for easy loading and unloading of test animals. The aerosol is delivered through a straight tube in the center of the chamber, therefore creating an efficient aerosol delivery.

Restraint Tube

Exposure Controls

The Exposure System Control Unit controls several separate functions. Air and vacuum controls allow the user to balance the air flowing into the exposure chamber so as to maintain a net negative pressure in the chamber. The air operated controls are: master air, nebulizer, diluter, and by pass. Vacuum operated functions are: Master vacuum, impactor, filter #1, filter #2, and chamber pressure. With the exception of the master air and master vacuum each of the above controls are associated with a flow meter so that precise flow can be determined. In addition to the previously mentioned functions, there is also a chamber pressure gauge which will alert users to changes in chamber pressure. Pressure gauges also monitor impactor, filter #1 and filter #2 functions to easily determine if a restriction has occurred during the sampling process.

Small Animal Restraints

The Small Animal Restraints hold the rodents in Lexan restraint tubes that feature precision machined Positive Flow By nose pieces. When placed in the chamber ports, the nose pieces connect with an o-ring seal to the inlet plenum of the chamber body. A second o-ring seals the nose pieces to the exhaust plenum of the chamber. Each nose piece has a series of exhaust jets strategically located behind the nose of the rodent. While in operation, each rodent receives a fresh, continuous stream of the aerosolized test article. The aerosol stream is drawn past the animal’s nose and into the exhaust jets where it is finally directed into the exhaust plenum of the exposure chamber. This design completely eliminates the possibility of re-breathing by the rodents. With the In-Tox Products Small Animal Exposure System there is no possibility that the rodents can breathe any test article exhaled by a rodent in an adjacent port.Type your paragraph here.

Tel: +1.505.832.5107

P.O. Box 2070, Moriarty, NM 87035 us

Exposure System Package

The In-Tox Products Small Animal Exposure System is a state of the art platform for exposing rodents to atmospheres of aerosolized test articles. The unique design of the system produces repeatable, stable spatial and temporarilly distributed aerosols directly to the breathing zone of the test rodent. 

The Small Animal Exposure System is comprised of several major components:

1 Exposure Chamber
1 Exposure Control Cabinet
1 Set of Complete Rodent Restraint Tubes
1 Lovelace Nebulizer
1 Mercer Impactor
1 47mm In-Line Filter Holder
1 Passive Air Filter
1 5/8" Aerosol Mixer
The Package also includes all of the necessary tubing lines and connections needed to operate the system as well a 1 year warranty.

Large Animal Restraints

In-Tox Products manufactures Large Animal Restraints for Inhalation Exposure studies.

Listed below are some of the standard configurations of restraints, however In-Tox Products has the capability of manufacturing restraints to the users specifications.

Complete Restraint

Inhalation Chambers manufactured by I.T.P. are recognized for their ability to deliver the aerosol directly to the respiratory tract and for delivering a precise amount of aerosol to the lung. The chambers are designed so they can be used for biological or toxicology studies.

In-Tox Products' Chambers are completely self-contained and sealed against leakage. They have been used outside of a bio-safety enclosures, however, I.T.P. recommends using a bio-safety enclosure when using toxic materials.

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